Okay so first of all, here are the stats for all playthroughs (NG0 - NG7):

Enemy Health: (x1.25) - (x1.5) - (x2) - (x2.25) - (x2.5) - (x2.75) - (x3) - (x3.25)
Enemy Stamina: x1.3
Enemy Damage: (x0.5) - (x0.6) - (x0.6) - (x0.6) - (x0.7) - (x0.8) - (x0.9) - (x1)
Enemy Damage Resist: (x1) - (x1.1) ->[for the rest starting from NG1]
Enemy Status Resist: (x1) - (x1.2) ->[for the rest starting from NG1]
Rune Multiplier: (x5) - (x7) - (x10) - (x15) - (x20) ->[for the rest starting from NG4] It look like a crazy value but when you are above level 400 even with 15/20 times more runes you still feel like you are stuck.
Enemy Poise Damage received: x1
Player Stamina Damage received: x1

Talisman changes:

Crimson Amber Medallion: Health bonus increased to 15%/20%/25% for versions base/+1/+2
Cerulean Amber Medallion: FP bonus increased to 15%/20%/25% for versions base/+1/+2
Viridian Amber Medallion: Stamina bonus increased to 15%/20%/25% for versions base/+1/+2
Blessed Dew Talisman: Regeneration increased to 5HP/s
Arsenal Charm: Bonus Load increased to 15%/20% for versions base/+1
Great Jar's Arsenal: Bonus Load increased to 25%
Dragoncrest Shield Talisman: Damage negation increased to 10%/15%/20% for versions base/+1/+2
Dragoncrest Greatshield Talisman: Damage negation increased to 25%
Spelldrake/Flamedrake/Boltdrake/Haligdrake Talisman: Damage negation increased to 15%/20%/25% for versions base/+1/+2
Pearldrake Talisman: Damage negation increased to 5%/10%/15% for versions base/+1/+2
Dagger Talisman: Crit Damage bonus increased to 25%
Twinblade Talisman: Damage bonus increased to 100% for the final attack
Axe Talisman: Damage bonus increased to 20%
Faithful's Canvas Talisman: Incantation bonus increased to 10%
Flocks Canvas Talisman: Incantation bonus increased to 15%
Warrior Jar Shard: Skill damage bonus increased to 15%
Shard of Alexander: Damage bonus increased to 20%
Blue Dancer charm: Max damage bonus increased to 30% (damage calculation formula remains the same)
Magic/Fire/Lightning/Sacred Scorpion Talisman: Damage bonus increased to 20%, removed increased damage received for the player
Red-Feathered Branchsword: Damage bonus increased to 50%
Blue-Feathered Branchsword: Damage negation increased to 70%
Ritual Sword Talisman: Damage bonus increased to 30%

The rest of the Talismans remains unchanged. These are the only changes that I made so far.
I changed the talismans that I thought were just very weak and not worth using a slot, they now should be worth considering. Also tweaked some that were decent, but only a little bit.

I've been playing this version of the game for some time now and I think I balanced it pretty well.
Enemies are Tough. Have tons of HP but also deal less damage so the fights are longer and more interesting. As for the boss fights player needs to hit the boss more times, evade more but is also punished less for a bad roll or dodge. I think this also allows to learn the game better, because you actually learn by repeating correct rolls/evades/finding openings.It's just plain nonsense to get killed by a single attack. Also the changes to Talismans allow for some interesting builds for player at every skill level.
Also this version of the regulation.bin actually makes it possible to get max level in some reasonable time. I for example don't have 1000h to farm in a single playthrough just to get it.

Just a reminder: DON'T USE THIS regulation.bin on multiplayer and online. Play offline and disable your Easy Anti Cheat first.
I may also add some changes later on but for now I think it's fine.

How to install:
1. In game menu switch to offline mode.
2. Backup your regulation.bin (it's here steamapps\common\ELDEN RING\Game)
3. Disable Easy-Anti Cheat (use this https://www.nexusmods.com/eldenring/mods/90)
4. Copy my regulation.bin into your Game folder
5. Play